Full list of publications can be found on Pubmed and Google Scholar.
Selected Publications:
1. ALS and Frontotemporal Dementia (FTD)
Single-nucleus sequencing reveals enriched expression of genetic risk factors in extratelencephalic neurons sensitive to degeneration in ALS
Limone F*, Mordes DA*, Couto A, Joseph BJ, Mitchell JM, Therrien M, Ghosh SD, Meyer D, Zhang Y, Goldman M, Bortolin L, Cobos I, Stevens B, McCarroll SA, Kadiu I, Burberry A, Pietiläinen O, Eggan K. Nature Aging. 2024.
Pluripotent stem cell strategies for rebuilding the human brain
Limone F, Klim JR, Mordes DA. Frontiers in Aging Neuroscience, 2022.
Absence of Survival and Motor Deficits in 500 Repeat C9ORF72 BAC Mice
Dipeptide repeat proteins activate a heat shock response found in C9ORF72-ALS/FTLD patients
2. Movement Disorders and Alpha-synuclein Pathology
Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism
Familial Parkinson's point mutation abolishes multiple system atrophy prion replication
Kinetics of α-synuclein prions preceding neuropathological inclusions in multiple system atrophy
3. DNA Damage Response Signaling
Two familial ALS proteins function in prevention/repair of transcription-associated DNA damage