Full list of publications can be found on Pubmed and Google Scholar.
Selected Publications:
1. ALS/Frontotemporal Dementia (FTD) and Stem Cell Models of Disease
C9ORF72 poly-PR disrupts expression of ALS/FTD-implicated STMN2 through SRSF7
Wang KW*, Smeyers J*, Eggan K, Budnik B, Mordes DA. ACTA Neuropathologica Comm., 2025.
Single-nucleus sequencing reveals enriched expression of genetic risk factors in extratelencephalic neurons sensitive to degeneration in ALS
Limone F*, Mordes DA*, Couto A, Joseph BJ, Mitchell JM, Therrien M, Ghosh SD, Meyer D, Zhang Y, Goldman M, Bortolin L, Cobos I, Stevens B, McCarroll SA, Kadiu I, Burberry A, Pietiläinen O, Eggan K. Nature Aging. 2024.
Pluripotent stem cell strategies for rebuilding the human brain
Limone F, Klim JR, Mordes DA. Frontiers in Aging Neuroscience, 2022.
Absence of Survival and Motor Deficits in 500 Repeat C9ORF72 BAC Mice
Mordes DA*, Morrison BM*, Ament XH, Cantrell C, Mok J, Eggan P, Xue C, Wang J, Eggan K, Rothstein JD. Neuron, 2020.
Two familial ALS proteins function in prevention/repair of transcription-associated DNA damage
2. Neuropathology of Alpha-synucleinopathies and Additional Neurodegenerative Diseases
Phosphorylation of tau at a single residue inhibits binding to the E3 ubiquitin ligase, CHIP
Nadel CM, Pokhrel S, Wucherer K, Oehler A, Thwin AC, Basu K, Callahan MD, Southworth DR, Mordes DA, Craik CS, Gestwicki JE. Nature Communications. 2024.