Daniel Mordes, MD, PhD

Assistant Professor, Dept. of Pathology
M_IND (Neurodegenerative Dis)

Dr. Daniel Mordes is a neuropathologist focused on understanding neurodegenerative diseases, including ALS, frontotemporal dementia, and Parkinson's disease. He is the Stuart Lindsay Professor in Experimental Pathology IV in the Department of Pathology and an Assistant Professor in the Institute for Neurodegenerative Diseases (IND) at UCSF. His research group integrates human stem cell-derived neuronal models and patient brain samples to study neurodegeneration at the Mission Bay campus. Currently, his research support includes the NINDS, Target ALS, The Frick Foundation for ALS Research, The Association for Frontotemporal Degeneration, and the Weill Neurohub Alliance for Therapies in Neuroscience. Dr. Mordes completed clinical training in neuropathology at Massachusetts General Hospital and post-doctoral training in stem cell biology and neuroscience with Kevin Eggan at Harvard University and the Broad Institute, and served as a neuropathologist for the Harvard Brain Tissue Resource Center (Brain Bank).

Publications

Publisher Correction: Exome sequencing in amyotrophic lateral sclerosis implicates a novel gene, DNAJC7, encoding a heat-shock protein.

Nature neuroscience

Farhan SMK, Howrigan DP, Abbott LE, Klim JR, Topp SD, Byrnes AE, Churchhouse C, Phatnani H, Smith BN, Rampersaud E, Wu G, Wuu J, Shatunov A, Iacoangeli A, Khleifat AA, Mordes DA, Ghosh S, ALSGENS Consortium , FALS Consortium , Project MinE Consortium , CReATe Consortium , Eggan K, Rademakers R, McCauley JL, Schüle R, Züchner S, Benatar M, Taylor JP, Nalls M, Gotkine M, Shaw PJ, Morrison KE, Al-Chalabi A, Traynor B, Shaw CE, Goldstein DB, Harms MB, Daly MJ, Neale BM

Exome sequencing in amyotrophic lateral sclerosis implicates a novel gene, DNAJC7, encoding a heat-shock protein.

Nature neuroscience

Farhan SMK, Howrigan DP, Abbott LE, Klim JR, Topp SD, Byrnes AE, Churchhouse C, Phatnani H, Smith BN, Rampersaud E, Wu G, Wuu J, Shatunov A, Iacoangeli A, Al Khleifat A, Mordes DA, Ghosh S, ALSGENS Consortium , FALS Consortium , Project MinE Consortium , CReATe Consortium , Eggan K, Rademakers R, McCauley JL, Schüle R, Züchner S, Benatar M, Taylor JP, Nalls M, Gotkine M, Shaw PJ, Morrison KE, Al-Chalabi A, Traynor B, Shaw CE, Goldstein DB, Harms MB, Daly MJ, Neale BM

Propagation of prions causing synucleinopathies in cultured cells.

Proceedings of the National Academy of Sciences of the United States of America

Woerman AL, Stöhr J, Aoyagi A, Rampersaud R, Krejciova Z, Watts JC, Ohyama T, Patel S, Widjaja K, Oehler A, Sanders DW, Diamond MI, Seeley WW, Middleton LT, Gentleman SM, Mordes DA, Südhof TC, Giles K, Prusiner SB