
Staff Research Associate
M_IND (Neurodegenerative Dis)
+1 415 502-7072
Why I work at the IND: Neurodegenerative diseases affect millions of people worldwide. I feel privileged to play even a minor role in helping those people.
Publications
Comprehensive mapping of synaptic vesicle protein 2A (SV2A) in health and neurodegenerative diseases: a comparative analysis with synaptophysin and ground truth for PET-imaging interpretation.
Acta neuropathologica
Phosphorylation of tau at a single residue inhibits binding to the E3 ubiquitin ligase, CHIP.
Nature communications
Severe neurodegeneration in brains of transgenic rats producing human tau prions.
Acta neuropathologica
Phosphorylation of a Cleaved Tau Proteoform at a Single Residue Inhibits Binding to the E3 Ubiquitin Ligase, CHIP.
bioRxiv : the preprint server for biology
Kinetics of a-synuclein prions preceding neuropathological inclusions in multiple system atrophy.
PLoS pathogens
Multiple system atrophy prions retain strain specificity after serial propagation in two different Tg(SNCA*A53T) mouse lines.
Acta neuropathologica
Structural heterogeneity and intersubject variability of Aß in familial and sporadic Alzheimer's disease.
Proceedings of the National Academy of Sciences of the United States of America
Familial Parkinson's point mutation abolishes multiple system atrophy prion replication.
Proceedings of the National Academy of Sciences of the United States of America
Evidence for sortilin modulating regional accumulation of human tau prions in transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America
Kinetics of Human Mutant Tau Prion Formation in the Brains of 2 Transgenic Mouse Lines.
JAMA neurology
A novel vector for transgenesis in the rat CNS.
Acta neuropathologica communications
Guinea Pig Prion Protein Supports Rapid Propagation of Bovine Spongiform Encephalopathy and Variant Creutzfeldt-Jakob Disease Prions.
Journal of virology
Towards authentic transgenic mouse models of heritable PrP prion diseases.
Acta neuropathologica
Optimization of Aryl Amides that Extend Survival in Prion-Infected Mice.
The Journal of pharmacology and experimental therapeutics
Brain Aggregates: An Effective In Vitro Cell Culture System Modeling Neurodegenerative Diseases.
Journal of neuropathology and experimental neurology
Prion Disease Induces Alzheimer Disease-Like Neuropathologic Changes.
Journal of neuropathology and experimental neurology
Evidence for a-synuclein prions causing multiple system atrophy in humans with parkinsonism.
Proceedings of the National Academy of Sciences of the United States of America
Propagation of prions causing synucleinopathies in cultured cells.
Proceedings of the National Academy of Sciences of the United States of America
Different 2-Aminothiazole Therapeutics Produce Distinct Patterns of Scrapie Prion Neuropathology in Mouse Brains.
The Journal of pharmacology and experimental therapeutics
White matter involvement in sporadic Creutzfeldt-Jakob disease.
Brain : a journal of neurology
Transmission of multiple system atrophy prions to transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America
Drug resistance confounding prion therapeutics.
Proceedings of the National Academy of Sciences of the United States of America
Biaryl amides and hydrazones as therapeutics for prion disease in transgenic mice.
The Journal of pharmacology and experimental therapeutics
Convergent replication of mouse synthetic prion strains.
The American journal of pathology
Chimeric elk/mouse prion proteins in transgenic mice.
The Journal of general virology
Purified and synthetic Alzheimer's amyloid beta (Aß) prions.
Proceedings of the National Academy of Sciences of the United States of America
Identification of I137M and other mutations that modulate incubation periods for two human prion strains.
Journal of virology
Spontaneous generation of rapidly transmissible prions in transgenic mice expressing wild-type bank vole prion protein.
Proceedings of the National Academy of Sciences of the United States of America
Spontaneous generation of anchorless prions in transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America